For my first two pastrami cooks I used prime brisket which I corned myself. I used Meathead's Almost Katz's rub recipe, but smoked to 170F internal using plum wood, then finishing off @ 195 for 4 hours in the sous vide. I did another batch skipping the sous vide and smoking to 205F internal. That was tasty but on the dry side. For this cook, I'm using corned beef flats I bought on sale after St Patty's Day last which I have soaked for 8 hrs and now it's been in the refer since last night with the rub on. I will smoke it again using plum wood to 170F internal and finish it off in the sous vide. Drooling in anticipation
QVQ is definitely the way to go with pastrami. Much better moisture retention and overall finish. The final smoking becomes the cherry on the sundae, there for bark and flavor. No need to worry about over shooting your temps.
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